Queen Square Centre for Neuromuscular Diseases
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- The UK’s first dedicated inpatient centre for people with complex neuromuscular disorders has been officially opened by leading healthcare advocate Sir Robert Francis
- The largest CNMD team to date ran the Bupa London 10,000 on 25th May to raise funds for the Centre. Please click here to donate.
- The dawn of translational optogenetics: Bryson et al. restored muscle function in a mouse model of peripheral nerve injury
- NIHR award MRC Centre for Neuromuscular Diseases £450,000 for research
- Arimoclomol has showed promise as a treatment for the most common type of inflammatory myopathy in adults over age 50 in a 1-year, phase IIa, "proof-of-concept" study
- MRC Centre featured in UCLH BRC Infrastructure Report
- Genomics England whole genome sequencing
- New sister centre partnership with the University of Iowa Department of Neurology
The Studentship Programme
4-year PhD program for Basic Scientists:
Year 1. 6 week orientation. Visit
laboratories of PIs. Each lab present details of potential 3 month
rotation projects. 3 x 3 monthly attachments to individual labs covering
at least 2 of each general subject areas in neuromuscular disease i.e.
molecular/genetics, cellular, systems/imaging. After the 3 monthly
attachments students chose a PhD project.
All students attend 6 week long orientation including introductory seminars on
neuromuscular disorders (in UCL this will be linked to the current MSc
in Clinical Neurosciences in Institute of Neurology). They will also
have the opportunity to attend meetings and seminars of the Centre as
Year 2-4. 3 year PhD in lab of choice. Many of the projects will not be based only in one laboratory as many of the PhD projects offer the opportunity to work between different laboratories on projects which reflect collaborations between various PIs in the MRC centre.
Mandatory each year (for 4 years):
a. Attend weekly journal club in respective laboratory (PI lead)
b. Attend programme of MRC neuromuscular centre seminars.
c. Two weeks dedicated generic training per year (from current courses offered in on statistics, research presentation, scientific writing, information technology, computer programming and experimental design, animal licensing, training in written and oral communication etc).
d. Maintain mandatory postgraduate log.
e. Quarterly meeting with both supervisors with review of log book and regular meeting (at least monthly) with primary supervisor. Annual independent review.
f. Attend one clinical/pathological meeting monthly (relevant to personal research).
g. Attend joint meetings of Centre researchers.
3 year Doctoral Training Programme for Clinical Scientists:
Years 1-3 3 year PhD in laboratory or
clinical research facility of choice. This may mean working in more than
one laboratory clinical research facility as many of the projects will
be collaborations between various PIs in the MRC centre.
Mandatory each year (for 3 years)
a. to g. as above for doctoral training programme for scientists plus
h. attend weekly outpatient clinic (half day) in rotation through all neuromuscular specialist clinics (adult muscle, paediatric neuromuscular disease, peripheral nerve, neuropathic pain, neurogenetics, cardiomyopathy, mitochondrial disease and clinical neurophysiology). Option to organize attachment at other site for exposure to specific specialized clinics.
i. weekly neuromuscular clinico-pathological participation (in rotation adult muscle, paediatric muscle, nerve).
j. Attend regular muscle pathology meeting
k. Attend regular nerve and muscle MRI meetings
l. (London) Attend monthly pan-London nerve clinico-pathology meeting