Eric P Hoffman, PhD Dr. Hoffman has been involved in translational human molecular genetics, and applications of genomics to health problems since the mid 1980’s. He worked with Louis Kunkel as his first post-doc, and with Anthony Monaco and Michele Koenig identified the Duchenne muscular dystrophy gene and protein, dystrophin. Other accomplishments include identification of the periodic paralysis gene in humans and horses, genetic causes of recurrent pregnancy loss, mapping the Rett syndrome gene, and applications of microarrays to muscle disease. He has over 300 publications, and is among the most highly cited researchers in muscle disease. Dr. Hoffman received his PhD in Genetics from Johns Hopkins University in 1986. He was then faculty at Harvard Medical School, and University of Pittsburgh School of Medicine. In 1999 he moved to Children’s National Medical Center in Washington DC to establish the Research Center for Genetic Medicine. The primary goal of this Center is to create interdisciplinary research programs capable of capitalizing on genome-enabled research approaches, and then rapidly translate the advances in understanding of disease pathogenesis to improved patient care. Duchenne muscular dystrophy remains his laboratory’s focus of research, with additional research projects on Limb-girdle muscular dystrophies, and inactivity and metabolic syndrome. His Center in Washington is committed to facilitating research nationally and internationally, and the Center houses six federally funded genomics and proteomic cores to provide research services to outside investigators. Coordinated research programs in Dr. Hoffman’s Center include the Wicker Project for Muscular Dystrophy, and NIH-funded Center grants in Muscular dystrophy, and rehabilitation research. Dr. Hoffman also serves as the Scientific Director of the Cooperative International Neuromuscular Research Group (CINRG), an active clinical trial network with 21 sites in 10 countries. |
Contact detailsResearch Center for Genetic Medicine Phone: 202 476 6011 Email: ehoffman@cnmcresearch.org Links: Wellstone Muscular Dystrophy Center: National Center for Medical Rehabilitation Research: Cooperative International Neuromuscular Research Group (CINRG):
Publications: 1: Hoffman EP, Monaco AP, Feener CC, Kunkel LM. Conservation of the Duchenne muscular dystrophy gene in mice and humans. Science. 1987 Oct 16;238(4825):347-50. PMID: 3659917 [PubMed - indexed for MEDLINE] 2: Hoffman EP, Brown RH Jr, Kunkel LM. 3: Hoffman EP, Fischbeck KH, Brown RH, Johnson M, 4: Bakay M, Wang Z, Melcon G, Schiltz L, Xuan J, 5: Chen YW, Zhao P, Borup R, Hoffman EP. 6: Seo J, Bakay M, Chen YW, Hilmer S, 7: Chen YW, Nagaraju K, Bakay M, McIntyre O,
9: Hoffbuhr K, Devaney JM, LaFleur B, Sirianni N, 10: Rudolph JA, Spier SJ, Byrns G, Rojas CV, 11: Rojas CV, Wang JZ, Schwartz LS, Hoffman EP, 12: Pegoraro E, Whitaker J, Mowery-Rushton P, 13: Lanasa MC, Hogge WA, Kubik C, Blancato J, 14: Zoeller RF, Ryan ED, Gordish-Dressman H, 15: Pistilli EE, Devaney JM, Gordish-Dressman H, 16: Spurney CF, Knoblach S, Pistilli EE, 17: Kesari A, Pirra LN, Bremadesam L, McIntyre O, 18: Nagaraju K, Rawat R, Veszelovszky E, 19: Hoffman EP. |
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